Apigenin is a flavonoid contained in the aqueous extract of Chamomile. This flavonoid has demonstrated significant anxiolytic activity.
- The methanolic extract of M. recutita demonstrated significant neuroprotective activity.
- Protected the brain against aluminum fluoride-induced oxidative stress.
At doses in excess of 50 and 100 mg/kg the essential oil of M. recutita resulted in a significant increase in the numbers of spontaneous locomotor activities, inducing anxiogenic activity (causing anxiety).
Disease / Symptom Treatment
M. chamomilla significantly reduced Depression Rating scores over time.
- M. chamomilla has been shown clinically effective for the treatment of generalized anxiety disorder (GAD).
Title: Pharmacotherapeutic Potential of Natural Products in Neurological Disorders
Author(s): Amritpal Singh SaroyaJaswinder Singh
Institution(s): Herbal Consultant Mohali India; Department of Pharmacology Sri Guru Ram Das Institute of Medical Science Amritsar India
Publication: Springer Nature Singapore
Date: 20 June 2018
Introduction: Natural Products have always played a pivotal role as sources for drug lead compounds. This book is aimed at providing inside purview of the scope of natural products (including herbal and marine) in the possible treatment of neurological disorders. The book explains pre-clinical neuropharmacological investigations done on herbs including Bacopa monnieri, Hypericum perforatum, Passiflora incarnata, Scutellaria baicalensis and Piper methysticum. It provides a comprehensive overview of the role of phytoconstituents like huperzine, curcumin, Salvinorin A, bioflavonoids, sulforaphane, tanshinone IIA, tetramethylpyrazine, tetrahydrocannabinol, and cannabidiol in the treatment of neurological disorders. The book provides a modern concept of herbal medications, neuropharmacology of marine bioactive products and Ayurvedic formulations, herbal drugs with abuse potential and neurotoxic mycotoxins.
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